Which vitamin K dependent factors are essential for blood coagulation?

The correct answer identifies factors that are crucial for the coagulation cascade and are specifically dependent on vitamin K for their synthesis in the liver. Vitamin K is essential for the post-translational modification of these coagulation factors, which involve a process called carboxylation. This modification is critical for their functional activity in coagulation.

Factors 2, 7, 9, and 10 are all vitamin K dependent. Factor 2, also known as prothrombin, is integral to the coagulation process as it is converted into thrombin, which plays a key role in the formation of a fibrin clot. Factor 7 is involved in the extrinsic pathway of coagulation, activating factors 10 and 9. Factor 9 is part of the intrinsic pathway, and its activation leads to the activation of factor 10. Factor 10, once activated, plays a major role in completing the coagulation cascade.

These factors are critically important in the control of bleeding and ensuring that blood coagulation occurs effectively when necessary. The importance of vitamin K in this context underlines its role in maintaining hemostatic balance.

Other options do not include all the necessary vitamin K dependent factors or contain factors that are not vitamin K dependent