Which of the following options describes a property of Docetaxel?

Prepare for the MRCS Exam with our study quizzes. Practice with multiple choice questions that include detailed hints and explanations to reinforce your learning. Equip yourself with the knowledge needed to excel in your examination!

Docetaxel is a chemotherapeutic agent classified as a taxane. Its primary mechanism of action is the disruption of microtubule formation. By binding to the beta-tubulin subunit of microtubules, Docetaxel prevents their depolymerization, which is essential for proper mitotic spindle function during cell division. This results in the stabilization of microtubules and effectively halts the cell cycle, ultimately leading to apoptosis in rapidly dividing cancer cells.

The other options do not accurately reflect the mechanism of action for Docetaxel. Alkylating agents work by adding alkyl groups to DNA, causing cross-linking and damage, while topoisomerase inhibitors interfere with the action of the topoisomerase enzymes that are crucial for DNA replication and transcription. Antimetabolites mimic the natural substances in the body and inhibit metabolic pathways necessary for DNA and RNA synthesis, but do not describe the action of Docetaxel.

Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy