Which of the following is an example of the usage of Anti-VEGF drugs?

Anti-VEGF drugs, which inhibit vascular endothelial growth factor (VEGF), play a crucial role in cancer treatment by blocking the formation of blood vessels that supply tumors, thereby restricting their growth and metastasis. The effectiveness of anti-VEGF agents is particularly well-documented in colorectal cancer, where they are often used in combination with chemotherapy. These drugs, such as bevacizumab, are integral in managing advanced or metastatic colorectal cancer, as they help to shrink tumors and improve patient outcomes by restricting their blood supply.

While anti-VEGF therapies are researched and utilized in other cancers like breast, prostate, and lung cancers, their primary, established role is in colorectal cancer treatment. The options represent different malignancies where various therapeutic modalities might be employed, but the strong association of anti-VEGF drugs with colorectal cancer highlights its significance as the correct answer in this context.