Which of the following is a common indication of meconium ileus in neonates?

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Meconium ileus is a condition often associated with cystic fibrosis and is characterized by the obstruction of the intestines due to thick, sticky meconium. A hallmark sign of meconium ileus in neonates is bilious vomiting. This occurs when the distal intestine becomes obstructed, preventing the passage of intestinal contents. As a result, bile, which is normally secreted into the intestine, backs up and is vomited. The presence of bilious vomiting indicates a blockage beyond the duodenum, suggesting a serious underlying issue such as meconium ileus.

Other symptoms, while they can occur in neonates with various gastrointestinal issues, are not as directly indicative of meconium ileus. For instance, failure to thrive can be seen in various conditions that affect feeding and absorption, and dehydration can arise from numerous situations including vomiting but are not specific to meconium ileus. Jaundice, which generally indicates liver dysfunction or hemolysis, is not typically associated with meconium ileus but can occur in other contexts. Thus, bilious vomiting stands out as a clear, common indication of meconium ileus in the neonatal population.

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