Which nerve supplies the webspace of the first and second toes?

The nerve that supplies the webspace of the first and second toes is the deep peroneal nerve, specifically its medial branch. This nerve is responsible for providing sensory innervation to the skin between the big toe and the second toe, making it essential for the sensation in that specific area.

The deep peroneal nerve emerges from the common peroneal nerve and descends alongside the anterior compartment of the leg. It innervates various muscles in that area before reaching the foot, where it continues as the medial branch to supply the webspace. This function is crucial for activities that involve proprioception and tactile feedback from the toes, contributing to balance and coordination.

Understanding this pathway and its role can help one appreciate why the deep peroneal nerve is associated with the sensation in the described webspace, which underscores its importance in both normal foot function and potential clinical diagnoses related to nerve injuries or entrapments.