Which nerve is responsible for taste sensation in the anterior two-thirds of the tongue?

The facial nerve is responsible for taste sensation in the anterior two-thirds of the tongue, making it the correct choice. This nerve carries taste fibers from taste buds located in this region through its chorda tympani branch, which merges with the lingual nerve, also carrying general sensation.

Understanding the role of each nerve helps clarify why this is the right answer. The vagus nerve primarily innervates structures in the throat and doesn't contribute to taste in the anterior tongue. The glossopharyngeal nerve is responsible for taste sensation in the posterior one-third of the tongue. The hypoglossal nerve primarily controls motor functions of the tongue and does not play a role in taste sensation. This anatomical distinction is crucial for recognizing the correct nerve responsible for taste in the anterior portion of the tongue.