Which anaesthetic is mostly used for rapid sequence induction?

Rapid sequence induction is a technique used primarily for patients at risk of aspiration during general anaesthesia. The goal is to facilitate rapid and effective intubation while minimizing the time between administering the induction agent and securing the airway.

Sodium thiopentone is a barbiturate that acts as a potent and rapid-acting anaesthetic agent, producing an anaesthetic state within seconds of administration. It is well-suited for rapid sequence induction because it facilitates the quick onset of unconsciousness and allows for a seamless transition to intubation. Additionally, sodium thiopentone is known for its favorable properties in terms of cardiovascular stability, which is particularly beneficial in emergency settings.

While agents such as etomidate and propofol are also used in induction, they each have specific characteristics that may make them less ideal in certain scenarios. For example, etomidate is excellent in minimizing cardiovascular effects and providing rapid onset but lacks analgesic properties. Propofol has a rapid onset and allows for quick recovery but may lead to hypotension, which is a concern in some patients. Ketamine is generally used for its analgesic properties and dissociative effects, making it preferable in certain patient populations but not typically the first choice for rapid sequence induction.