What sequence correctly describes the passage of CSF through the ventricular system?

The sequence that correctly describes the passage of cerebrospinal fluid (CSF) through the ventricular system begins in the lateral ventricles, moves to the third ventricle, and then flows into the fourth ventricle.

Initially, CSF is produced in the choroid plexus located within the lateral ventricles. It then flows through the interventricular foramen (also known as the foramen of Monro) into the third ventricle. Once in the third ventricle, the CSF may circulate and then drains into the fourth ventricle via the cerebral aqueduct (Aqueduct of Sylvius). From the fourth ventricle, CSF can enter the subarachnoid space, which surrounds the brain and spinal cord, providing cushioning and support.

Understanding this flow is crucial in clinical settings, as any disruption can lead to conditions such as hydrocephalus, where CSF accumulates due to blockage or malabsorption. The other provided sequences are inaccurate because they either misplace the order of the ventricles or suggest an impossible route of flow that does not conform to the established anatomy of the ventricular system.