What is the treatment for low-grade DCIS?

Low-grade ductal carcinoma in situ (DCIS) is a non-invasive breast condition characterized by abnormal cells in the milk ducts. The treatment for low-grade DCIS typically involves local excision, also known as lumpectomy, which aims to remove the cancerous cells while preserving as much healthy breast tissue as possible. This approach is often preferred for low-grade cases because it has been shown to have a favorable outcome and lower risk of recurrence when compared to more extensive surgeries, such as mastectomy.

Local excision allows for effective management of the condition while minimizing impact on the patient’s body and maintaining breast appearance. In many instances, it may be followed by radiation therapy to further reduce the risk of recurrence in the affected area, depending on specific risk factors and the patient's preferences.

Other treatment options, such as mastectomy, would be more appropriate in cases of higher-grade DCIS or when there are other concerning factors. Targeted therapy and hormone therapy are usually reserved for invasive breast cancers or specific cases where the cancer is hormone receptor-positive and has progressed beyond the in situ stage. Therefore, local excision represents the most suitable initial treatment for low-grade DCIS.