What is the recommended management for acute limb ischaemia occurring between 6 to 12 hours?

The recommended management for acute limb ischaemia occurring between 6 to 12 hours is angiography plus or minus intra-arterial thrombolysis. This approach is appropriate because, after 6 hours, there is still potential for limb salvage, but the situation is becoming increasingly urgent. Angiography allows for visualization of the vascular anatomy and can identify the site of occlusion. If a clot is found, intra-arterial thrombolysis can be utilized to dissolve the thrombus, improving blood flow to the affected limb.

Timely intervention is crucial in this timeframe, as delays may lead to irreversible tissue damage. The use of thrombolysis can potentially restore perfusion and prevent the need for more radical interventions such as amputation. By addressing the underlying blockage and re-establishing blood supply, it increases the chances of saving the limb.

Other options do not provide the necessary intervention for limb ischaemia at this stage. Cooling packs and observation might be suitable for less severe situations or if the condition were chronic, but they do not address the acute nature of the ischaemia. Immediate amputation would be excessive at this time, as it is generally reserved for cases where there is clear evidence of irreversible damage or gangrene. Physi