What is a contraindication for intraarterial thrombolysis?

Intraarterial thrombolysis is a procedure used to dissolve blood clots in arteries. Certain contraindications must be considered to minimize the risk of serious complications such as bleeding.

Having a history of cerebrovascular accident (CVA) within the past two months is a critical contraindication for intraarterial thrombolysis. This is primarily because recent CVA indicates that the vasculature may still be fragile or at risk for hemorrhagic complications. The physiological response to a thrombolytic agent in an area recently affected by a stroke can lead to significant bleeding, worsening the patient's condition.

Other factors such as diabetes mellitus, history of hypertension, or asthma do not have the same immediate risk profile in relation to the thrombolytic treatment. While these conditions may influence overall management or risk assessments for patients, they do not present the same level of urgency regarding the acute risk associated with recent vascular events.

Understanding the implications of recent CVA is vital when evaluating candidates for intraarterial thrombolysis, as safety and efficacy in such instances must be highly prioritized.