What does the acronym HARDUP help to remember in relation to normal gap acidosis?

The acronym HARDUP is specifically designed to aid in recalling the causes of normal gap acidosis, also known as non-anion gap metabolic acidosis. Normal gap acidosis is characterized by a decrease in bicarbonate levels without an increase in the anion gap. The components of the acronym stand for:

• Hyperalimentation

• Acetazolamide

• Renal tubular acidosis

• Diarrhea

• Ureterosigmoidostomy

• Pancreatic fistula

Each item in HARDUP indicates a potential cause of this condition, helping clinicians quickly remember the relevant factors when diagnosing and managing metabolic acidosis with a normal anion gap.

Understanding this acronym is crucial for medical professionals, especially surgeons and those preparing for exams like the MRCS, as it provides a systematic approach to diagnosing and treating patients presenting with acidosis, which can have various underlying etiologies. This knowledge is essential for guiding the appropriate therapeutic interventions and enhancing patient outcomes.