What does IV broad-spectrum antibiotics primarily aim to prevent in open fractures?

The primary aim of administering intravenous broad-spectrum antibiotics in the context of open fractures is to prevent infection. Open fractures expose the bone and surrounding tissues to bacteria from the environment, which significantly increases the risk of bacterial contamination and subsequent infection. Since infections in open fractures can lead to serious complications such as osteomyelitis, delayed healing, or even loss of limb, prompt administration of antibiotics is crucial to mitigate this risk.

Broad-spectrum antibiotics are particularly beneficial in this setting as they are effective against a wide range of potential pathogens, including both gram-positive and gram-negative bacteria. This diverse coverage is essential because it is often difficult to identify the exact type of bacteria present at the time of treatment.

Addressing the other options, while neuropathy and fracture non-union are important concerns in the management of fractures, they are not the direct focus of antibiotic therapy. Likewise, delayed healing may occur as a consequence of an infection, but the primary intervention with antibiotics is specifically aimed at preventing the infection itself. Thus, the rationale for using intravenous broad-spectrum antibiotics in open fractures revolves mainly around infection prevention.