What does IV broad-spectrum antibiotics primarily aim to prevent in open fractures?

Intravenous broad-spectrum antibiotics are primarily administered in the setting of open fractures to prevent infection. An open fracture, where the bone is exposed to the external environment, carries a significant risk of contamination by bacteria, which can lead to osteomyelitis (bone infection) and other complications.

The use of broad-spectrum antibiotics helps cover a wide range of potential pathogens, including both gram-positive and gram-negative bacteria, which is crucial given the variety of environmental bacteria that may enter through the wound at the time of injury. Effective prophylactic antibiotic therapy can significantly reduce the incidence of infections associated with open fractures, promoting better outcomes and fewer complications in surgical management.

While concerns such as neuropathy, fracture non-union, and delayed healing are valid in the context of fracture management, they are not the direct target of antibiotic therapy. Instead, the primary goal remains focused on infection prevention, which is a critical aspect of managing open fractures effectively.