In the context of metabolic acidosis, which of the following is NOT part of the HARDUP mnemonic?

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The HARDUP mnemonic is a helpful tool for remembering the causes of hyperchloremic metabolic acidosis. Each letter stands for a different condition that can lead to this type of acidosis. The conditions represented include:

  • H: Hyperalimentation
  • A: Acetazolamide

  • R: Renal tubular acidosis

  • D: Diarrhea

  • U: Ureteral diversion

  • P: Pancreatic fistula

In this mnemonic, liver dysfunction is not included as a cause of hyperchloremic metabolic acidosis, making it the correct answer for the question. Liver dysfunction primarily causes metabolic acidosis through different mechanisms, such as lactic acidosis or due to impaired gluconeogenesis. Therefore, the other options such as diarrhea, renal tubular acidosis, and ureteral diversion do represent conditions listed in the HARDUP mnemonic, while liver dysfunction does not, confirming it as the outlier in this specific context.

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